http://hdl.handle.net/11422/20547 Thu, 16 Apr 2026 03:15:06 GMT 2026-04-16T03:15:06Z http://hdl.handle.net/11422/29001 Title: Vitamina D em crianças e adolescentes com dermatite atópica em uma região ensolarada: níveis séricos e correlação com a gravidade Author(s)/Inventor(s): Andre, Adriana da Silva Diaz Advisor: Goudouris, Ekaterini Simoes Abstract: The fact that some studies show the role of vitamin D in both the epidermal barrier and the immune system has sparked the interest of many authors in establishing a relationship between its serum levels and some skin diseases, such as atopic dermatitis (AD). This observational study aimed to examine the serum vitamin D levels of children with atopic dermatitis and their correlation with disease severity, as well as to determine whether children with AD can be considered a risk group for vitamin D deficiency. Eighty serum 25(OH)D measurements were performed on 79 children with atopic dermatitis between seven months and 16 years of age between 2021 and 2023. Most patients (82%) presented with vitamin D insufficiency or deficiency, and patients with more severe AD had lower serum levels of 25(OH)D, although this correlation was not statistically significant. It was concluded that vitamin D deficiency was highly prevalent in children with atopic dermatitis living in a sunny region. Publisher: Universidade Federal do Rio de Janeiro Type: Dissertação Wed, 25 Feb 2026 00:00:00 GMT http://hdl.handle.net/11422/29001 2026-02-25T00:00:00Z http://hdl.handle.net/11422/28946 Title: Adaptação transcultural para o português brasileiro do questionário Parent-Report Form For Neonates And Toddlers (0-3 years of age) para avaliação de distúrbios de interação intestino-cérebro em pediatria Author(s)/Inventor(s): Lima, Ana Beatriz de Menezes Advisor: Land, Marcelo Gerardin Poirot Abstract: Functional gastrointestinal disorders (FGD), currently known as gut-brain interaction disorders (DGBI), are recognized as frequent and recurrent gastrointestinal symptoms involving different regions of the digestive tract. These disorders have great clinical and economic relevance, with a negative impact on the quality of life of the entire family, in addition to representing a large part of the demand for pediatric gastroenterology practices. Its diagnosis is based on the Rome IV criteria, translated through a questionnaire prepared by the Rome Foundation in English. The translation and cross-cultural adaptation of this instrument helps in the most appropriate diagnosis, providing a better quality of life for patients. Objective: to carry out the translation and cross-cultural adaptation of the questionnaire “Parent-Report Form For Neonates And Toddlers (0 To 3 Years)” R4PDQ (Rome IV Pediatric Diagnostic Questionnaire) – Neonates and Toddlers into Brazilian Portuguese, observing conceptual, item and semantic equivalences; evaluate acceptability and evaluate content validity index. Method: the process of translation and cross-cultural adaptation of the instrument was based on the universalist model, following the methodological steps proposed internationally, in addition to the translation guidelines recommended by the Rome Foundation: double translation, synthesis and back-translation, analysis by a committee of experts, proposition of a pre-final version, cognitive assessment, content validity index assessment (CVI - number of experts in agreement divided by the total number of experts) and proposition of the final version of the questionnaire. Result: The results of the translated and adapted questionnaire indicated agreement in the comparisons; cognitive assessment demonstrating good understanding and receptivity; CVI equal to 1. The final questionnaire and the favorable opinion of the Brazilian monitor in Rome were sent to the Foundation, with final approval of the questionnaire translated and adapted into Brazilian Portuguese. Conclusion: the translation and cross-cultural adaptation of the questionnaire “Parent-Report Form For Neonates And Toddlers (0-3 Years Of Age)” for assessing DGBI in Pediatrics into Brazilian Portuguese was successfully achieved and demonstrated to be understandable. This questionnaire may help and encourage new projects on DGBI in the pediatric population. Publisher: Universidade Federal do Rio de Janeiro Type: Dissertação Fri, 29 Nov 2024 00:00:00 GMT http://hdl.handle.net/11422/28946 2024-11-29T00:00:00Z http://hdl.handle.net/11422/28943 Title: Adaptação transcultural do questionário “Self-Report Form for Children and Adolescents (10 years of age and older)” para transtornos da interação intestino-cérebro em adolescentes brasileiros Author(s)/Inventor(s): Tomé, Thaís Moreno Advisor: Land, Marcelo Gerardin Poirot Abstract: Introduction: Disorders of gut-brain interaction (DGBIs) include a variety of recurrent gastrointestinal symptoms, not associated with structural or biochemical abnormalities that make their diagnosis difficult. They are evaluated based on clinical criteria defined by the Rome Foundation, which also develops diagnostic questionnaires. It is essential that they are validated and adapted for use in the target population. Objective: Perform the translation and cross-cultural adaptation of the questionnaires developed by the Roma Foundation for the diagnosis of DGBIs in children 4 years of age and older. Methods: The cross-cultural adaptation protocol followed theoretical references and guidelines from the Rome Foundation, with the following steps.: (i) Preparation; (ii) Forward Translation; (iii) Reconciliation; (iv) Backward translation; (v) Review of the backward translation; (vi) Cognitive debriefing; (vii) Calculation of the Item Content Validity Index; (viii) Final review and (ix) Approval by the Rome Foundation. Results: During the translation stage, priority was given to a version that would be easily understood by people from different parts of the country and social backgrounds, and that encompassed the largest number of regional expressions. In the backward translation, 85% of the items remained unchanged or had minor alterations, indicating adequate equivalence. The cognitive debriefing showed understanding above 90% in the first stage, demonstrating that the questionnaire is clear and easy to answer. After the evaluation of the 5 judges, the content validity index resulted in a value of 0.99, indicating the reliability of the cross-cultural adaptation and suitability of the questionnaire. Conclusions: The cross-cultural adaptation to Brazilian Portuguese of the diagnostic questionnaire for DGBIs in children over 4 years old was successful and officially approved by the Rome Foundation, enabling its use in local and global epidemiological studies. Publisher: Universidade Federal do Rio de Janeiro Type: Dissertação Thu, 10 Oct 2024 00:00:00 GMT http://hdl.handle.net/11422/28943 2024-10-10T00:00:00Z http://hdl.handle.net/11422/28927 Title: Transtorno de Estresse Pós-Traumático em profissionais de saúde atuantes em unidades de terapia intensiva pediátrica durante a pandemia de COVID-19 Author(s)/Inventor(s): Silami, Pedro Henrique Nunes Costa Advisor: Cunha, Antonio José Ledo Alves da Abstract: Background: professionals in Intensive Care Units (ICU) are at increased risk of developing mental health disorders, such as Posttraumatic Stress Disorder (PTSD). The COVID-19 pandemic has exacerbated this issue, particularly concerning adult ICU burdened with a high influx of critically ill patients. However, Pediatric ICU (PICU) have also received adult patients, their staff dealt with redeployment, and have faced the unfamiliar Pediatric Multisystem Inflammatory Syndrome associated with COVID-19. Previously, the estimated prevalence of PTSD in these professionals ranged from 13 to 24%, and since the extent of the impact on PICU workers remains unknown, the aim of this study is to the aim of this study is to estimate the prevalence of PTSD in PICU healthcare workers, determine this prevalence in specific subgroups based on demographic and occupational characteristics, and assess its relationship with social support and resilience. Methods: an observational, cross-sectional, multicenter study was conducted. Twenty-nine public and private PICU from across Brazil were invited to participate, comprising a total of 1,506 physicians, nurses, nursing technicians, and physical therapists. Demographic and occupational variables were collected, as well as organizational variables from each PICU. The outcome PTSD was assessed using the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) and defined as present when meeting DSM-5 diagnostic criteria. Results: with 1,084 respondents (a response rate of 72%), the prevalence of PTSD was 13%, with a median PCL-5 score of 14 (interquartile range [IQR] 7–23), although 26% to 53% of professionals exhibited some kind of symptomatology of posttraumatic stress, mainly intrusive symptoms. Their levels of resilience and social support were lower in those with more posttraumatic symptoms (p < 0.001 for all). Thirty-two percent of participants cared for adult COVID19 patients, with no difference in the prevalence of PTSD compared to others. Subgroups with higher PTSD prevalence included females (median 14 [IQR 7-24], p<0.01) and those with a previous history of mental health disorders (median 17 [IQR 10 12-26), p<0.001). Workers in public units also had more PTSD (14.8% vs. 10% in private units, p=0.03), with no differences in levels of resilience or social support. When asked about distressing professional events, such as a lack of resources or personal protective equipment, the PTSD subgroups and those in public units reported higher levels of distress. Conclusions: The prevalence of PTSD in PICU workers is comparable to that suggested by previous studies in adult ICU workers during the first peak of the COVID-19 pandemic in Brazil. Those with more symptoms had lower levels of social support and resilience, as well as more distress when reporting professional events. This suggests that organizational factors related to the institution also play a role beyond personal factors. Furthermore, certain subgroups, such as those with a history of mental health disorders, had a higher prevalence of PTSD, suggesting a focus on these subgroups to identify those in need of institutional support Publisher: Universidade Federal do Rio de Janeiro Type: Dissertação Fri, 20 Oct 2023 00:00:00 GMT http://hdl.handle.net/11422/28927 2023-10-20T00:00:00Z