Nanotecnologia e neurociência computacional: revisão de literatura

Abstract

This work is a standardized set of descriptive elements that consolidate this study through the theoretical field and in the search to answer questions about Nanotechnology and Computational Neuroscience in the field of cerebral arteriovenous malformations (AVM). AVM is a congenital disease with invasive treatment methods such as surgery, radio surgery, catheter embolization. In most cases, embolization fails to fully treat the lesion (only in 15% to 20% of cases) and the risk of branching the extraordinary vessels can lead to circulatory theft of normal areas of the brain. Depending on the location of the AVM, the irrigation deficit resulting from the extraordinary branching compromises important cognitive functions, therefore, there is a need for a more efficient and less invasive method to treat malformations. The importance of proposing an alternative for catheter embolization is evident, considering applications involving self-guided nanoparticles. The method for obtaining possible results will be through simulation with artificial intelligence. During the research, investigations will be carried out in the areas of nanotechnology and computational neuroscience, especially in the implementation of computational applications, together with the collection of information and data necessary for research on AVM. The challenge begins to collectively collect a bibliographic study on AVM. To this end, a large compendium of works is exposed that seeks to represent the implications and applications involving self-guided nanoparticles.