Coexistência de Síndrome de Sjögren e sarcoidose: revisão bibliográfica

Abstract

This work consists of a literature review on the concomitance of Sarcoidosis and Sjögren's syndrome (SS). Sarcoidosis is known to mimic Sjögren's syndrome, and its diagnosis has been included as an exclusion criterion in the diagnostic framework for SS established by the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR). However, numerous clinical cases and some case series have been published in the medical literature reporting the coexistence of both diagnoses. The possibility of synchronicity between these conditions in such reports has been supported by authors based on compatible clinical features, serological findings, and concomitant histopathological patterns. Furthermore, epidemiological studies on sarcoidosis have observed a higher prevalence of autoimmune conditions in these patients compared to the general population, including a greater prevalence of SS, suggesting a non-random association. Therefore, this literature review aims to narratively synthesize the main points from publications that investigated cases where sarcoidosis was considered not only to mimic SS but also to present evidence supporting the coexistence of both diagnoses.