Vitamina D em crianças e adolescentes com dermatite atópica em uma região ensolarada: níveis séricos e correlação com a gravidade

Abstract

The fact that some studies show the role of vitamin D in both the epidermal barrier and the immune system has sparked the interest of many authors in establishing a relationship between its serum levels and some skin diseases, such as atopic dermatitis (AD). This observational study aimed to examine the serum vitamin D levels of children with atopic dermatitis and their correlation with disease severity, as well as to determine whether children with AD can be considered a risk group for vitamin D deficiency. Eighty serum 25(OH)D measurements were performed on 79 children with atopic dermatitis between seven months and 16 years of age between 2021 and 2023. Most patients (82%) presented with vitamin D insufficiency or deficiency, and patients with more severe AD had lower serum levels of 25(OH)D, although this correlation was not statistically significant. It was concluded that vitamin D deficiency was highly prevalent in children with atopic dermatitis living in a sunny region.