Análise dos desfechos da administração orofaríngea de colostro em recèm-nascidos prematuros de muito baixo peso

Abstract

Introduction: Colostrum is the first secretion produced by the mammary glands, resent until the Tth day of hfe. It has important immunomodulatory components and protective factors that will contribute to the protection and development of the newbom. The oropharyngeal administration of colostrum (OAC) appears as a potential option for very low-birth-weight newborns (VLBW; <1500g). Objective: to analyze the clinical outcomes of VLBWs submitted to OAC. Methods: Retrospective longitudinal study. Non-probability sampling method. Inclusion criteria: VLBW's submitted to the OAC protocol. Exclusion criteria: VLBW s whose OAC data were not available or received no dose and death in the first days of life. The Mann-Whitney test was used to compare quantitative variables and Wilcoxon to assess the evolution of anthropometric values, with a significance level of 5% (p <0.05). Results: start of Enteral Nutritional Therapy (ENT) ( [1-1]); reach of full enteral feeding (11.0 [9.0-16.0]); recovery of birth weight (11 [7.0-14.0]). OAC onset at 3 days of life and the number of total doses 32.5 [21.0-44.0]. Significant difference in the weight in fewer days with a higher number of doses Cp = 9.07). The <ime to fall enteral feeding was significantly longer and the time for recovery of birth weight was significantly less when considering the onset <3 days (p = 0.023). Conclusions: OAC was associated with time to recover birth weight and time to full enteral feeding.