Desenvolvimento de um grampo de sutura metálico, biomimético e recoberto com substância ativa

Abstract

The instruments and procedures for suturing are constantly being improved, with innovations aimed at greater efficiency and medical safety. In this context, biomimicry is an inspiring technique for technical - scientific advances in this field. Thus, the objective of the research was to develop and manufacture a new conception of a metallic suture clip, bioinspired in the ancient knowledge of use of the mandibles of the ants in the suture. In the design of the clip, innovation and addition of coatings with antimicrobial agents were also considered, using sucupira and andiroba oils, and also to the design of a specific instrument for its application. The suture clip was designed based on the functioning of muscle fibers of the head of Atta laevigata. This was manufactured in real size, after development by computer simulation, and heat treated. Coatings were made on the metal surface, forming thin films with PLA or PCL and natural oils. These were characterized by thermal, chemical, cytotoxicity and microbiological analysis. The new suture clip demonstrated efficiency, practicality and safety. The coatings showed controlled release amid aqueous and antimicrobial action, a requirement for an efficient healing process. The application instrument was also bioinspired and developed so that it can be reused, reducing the cost of the mechanical suture technique.