Resposta ao corticosteroide em um caso de nefrite tubulointesticial aguda por leptospirose

Abstract

This case report aims to present basis for future cases, in which the inffection caused by Leptospira associated with acute renal injury, that did not present successful development after appropriate treatment, may be related to Tubulointersticial Nephritis that requires corticotherapy. A patient with important epidemiological evidence and Weil's Syndrome classic clinical presentation, with positive sorogical tests for leptospirosis, developed acute renal injury that demanded intermittent hemodialysis in the acute phase of the disease. However, in spite of the satisfactory clinical evolution following antibiotic therapy and hemodynamic support, the patient still had need of renal replacement therapy to survive. Due the uncommon outcome, renal biopsy was performed leading to Tubulointerstitial nephritis diagnosis, mostly acute, that required corticotherapy. After the appropriate therapy,the patient had hemodialysis suspended and progressed to conservative management of the chronic kidney disease.