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http://hdl.handle.net/11422/27333
| Especie: | Artigo |
| Título : | DAPK and P16 methylation and HPV and EBV infection in small cell carcinoma of cervix: a case report |
| Autor(es)/Inventor(es): | Furtado, Yara Lúcia Ribeiro, Fernanda Lattario Silveira, Filomena Aste Carvalho, Maria da Glória da Costa Almeida Filho, Gutemberg Leão de |
| Resumen: | Indisponível. |
| Resumen: | Purpose: Small cell carcinoma (SMCC) of the cervix is rare and aggressive tumor, often diagnosed in an advanced stage and their prognosis is generally poor. A case of SMCC showing Human Papillomavirus (HPV) and Epstein barr virus (EBV) infection and Death-associated protein kinase (DAPK) and p16 genes methylation is presented. A 74-year-old woman was diagnosed as having stage IB2 of SMCC. Methods: HPV and EBV infection and DAPK and p16 gene methylation were found using molecular approaches. Results: The sample was positive for HPV and EBV infection and showed DAPK and p16 promoter regions methylated Conclusion: Methylation of DAPK and p16 gene could be used as a molecular marker in cervical cancer. |
| Materia: | Proteínas quinases associadas com morte celular Papilomavírus humanos Neoplasias do colo do útero Death-associated protein kinases Human Papillomavirus Viruses Uterine cervical neoplasms HPV |
| Materia CNPq: | CNPQ::CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::GINECOLOGIA E OBSTETRICIA |
| Unidade de producción: | Instituto de Ginecologia |
| Editor: | Hilaris SRL |
| Es parte de: | Journal of Clinical Case Reports |
| Volumen: | 6 |
| Número: | 4 |
| Fecha de publicación: | 2016 |
| DOI: | 10.4172/2165-7920.1000781 |
| País de edición : | Bélgica |
| Idioma de publicación: | eng |
| Tipo de acceso : | Acesso Aberto |
| ISSN: | 2165-7920 |
| Aparece en las colecciones: | Ciências da Saúde |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| GLAlmeida_DAPK.pdf | 169.9 kB | Adobe PDF | Visualizar/Abrir |
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