Modelagem da variação intraindividual e interindividual na análise de índices autonômicos cardiovasculares não invasivos em sujeitos normais : o desafio da respiração

Abstract

This work proposes a method to model interindividual and intraindividual differences of cardiorespiratory variables used as autonomic nervous system indexes. Tested subjects inter- and intra-individual variations emphasized the need to consider respiratory influence when analyzing these variables. Therefore, this work also presents a new method, based on autoregressive modeling considering the concept of Granger causality, for removing respiratory influence and assessing the causal relationships between the RR interval and systolic blood pressure cardiovascular variables. Respiratory influence removal was effective. However, the proposed model for the studying causal relationships between two variables, considering signals with removed respiratory influence, should be used with caution.