Mastocitoses cutâneas: revisão de literatura

Abstract

Objective: To classify cutaneous mastocytosis to better understand its prognosis and establish appropriate treatment. Method: Literature review using the PubMed platform. Result: Mastocytosis is a rare disease characterized by the proliferation and accumulation of mast cells in the skin or other tissues. The skin is the most commonly affected organ. Approximately 100% of children and 80% of adults with mastocytosis present with cutaneous lesions. According to the classification proposed by the World Health Organization (WHO) in 2016, cutaneous mastocytosis can be subdivided into three subtypes: maculopapular cutaneous mastocytosis, diffuse cutaneous mastocytosis, and cutaneous mastocytoma. This subdivision is related to the disease’s prognosis and shows that lesions appearing in childhood are usually limited to the skin, whereas those arising in adulthood tend to have a more chronic course and require investigation for systemic mastocytosis. Conclusion: Understanding cutaneous mastocytosis and properly classifying it is crucial not only for the effective treatment of the condition but also for establishing its prognosis.