Efeito das condições de síntese sobre a morfologia de nanopartículas de amido e sua aplicação como carreador de fármaco

Abstract

This project aimed to develop and characterize biopolymeric and biodegradable nanoparticles synthesized by nanoprecipiation. Nanoparticle, both isolated and used in biopolymer films, were composed of corn starch. The parameters of the nanoprecipitation process that influence the physico-chemical, structural and morphological characteristics of the nanoparticles were studied. In order to evaluate the influence of nanoprecipitation parameters, nanoparticles and films were characterized by MEV, MET, AFM, FTIR and DRX. It was observed that the nanoparticles had different sizes and shapes and the films presented changes in the roughness and particle size.